Affron® is a premium quality saffron extract that is standardized to contain a minimum of ≥3.5% Lepticrosalides®, a complex of bioactive compounds that are responsible for the numerous beneficial and organoleptic properties of this amazing product.
These compounds have been extensively studied and have been shown to have a positive impact on mood, particularly in individuals who experience stress, anxiety, or depression symptoms.
1 million people worldwide benefit from Affron® to maintain a positive mood and mental balance every day.
– Pharmactive Biotech Products –
In a randomised, double-blind, placebo-controlled study (N=128) Affron® intake of 28mg/day for 4 weeks, significantly improved mood disorders, such as tension, anger, depression, fatigue and confusion.
The results of a meticulously conducted randomized, double-blind, and placebo-controlled research study involving a total of 68 participants have now unequivocally demonstrated the potential efficacy of Affron®, a natural extract, in the management and alleviation of anxiety and depressive symptoms among adolescents aged 12 to 16 years who have been experiencing mild-to-moderate symptoms.
The study, which was carried out over a period of eight weeks, produced overwhelmingly positive results from the perspective of the adolescent participants, paving the way for further investigation into the potential mechanisms underlying the beneficial effects of Affron® and its potential role in the treatment of this vulnerable population.
The findings of this research study provide a glimmer of hope for clinicians and families struggling to manage the often debilitating symptoms of anxiety and depression in adolescents and underscore the importance of continued research into the development of novel and effective treatments for mental health conditions.
Safranal, one of the main bioactive compounds of Affron®, showed an improvement of the quality of sleep through the increase of NREM sleep duration (Non-Rapid Eye Movement), the decrease of NREM sleep latency, and the enhancement of delta power activity of NREM sleep.
After single intake of Affron®, Crocin isomers are rapidly transformed into Crocetin, whose maximum serum levels are reached within 60-90 minutes. This suggests a faster action than other antioxidant molecules (such as Zeaxanthin, Lutein or Beta-Carotene).
Affron® acts mainly at two levels:
New randomized, double-blind, placebo-controlled study (N=160 adults) demonstrated that Affron® is well tolerated administered jointly with antidepressant drugs and is effective in helping to counter unremitted depression.
After 8-weeks of Affron® intake it has bee shown that:
